Galacto configured N-aminoaziridines: a new type of irreversible inhibitor of β-galactosidases.
نویسندگان
چکیده
A new type of galactose mimetics has been synthesized following a straightforward synthetic approach based on cyclohexene olefin aziridination reactions directed by hydroxyl substituents. These enantiomerically pure galacto-configured N-aminoaziridines are potent irreversible inhibitors of Aspergillus oryzae and Escherichia coliβ-galactosidases.
منابع مشابه
Galacto configured N-aminoaziridines: a new type of irreversible inhibitors of -galactosidases
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 20 شماره
صفحات -
تاریخ انتشار 2015